VINORELBINE RELATED COMPOUND A4-O-DEACETYLVINORELBINE TARTRATE USP STANDARD - Names and Identifiers
Name | Vinorelbine Ditartrate
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Synonyms | Nvb Navelbine Vinorelbin Bitartrate Pacilitaxel Navelbine tartrate Vinorelbine tartrate Vinorelbine tartarate Vinorelbine bitratrate Vinorelbine Ditartrate Vinorelbine bitartrate VinorelbineTartrateUsp28 VINORELBINE TARTRATE, USP Vinorelbine ditartrate salt Vinorelbine ditartaric acid VINORELBINE TARTRATE, NAVELBINE VINORELBINE TARTRATE USP STANDARD Vinorelbine tartrate usp standard Vinorelbineditartrate salt hydrate 5'-noranhydrovinoblastine tartrate VINORELBINEDITARTRATE SALT HYDRATE 3',4'-didehydro-4'-deoxy-c'-norvincaleukoblastine VINORELBINE RELATED COMPOUND A4-O-DEACETYLVINORELBINE TARTRATE USP STANDARD C'-norvincaleukoblastine,3',4'-didehydro-4'-dioxy-,(R-(R*,R*))-2,3-dihydroxy (3Ar,3A1R,4R,5S,5Ar,10Br)-Methyl 4-Acetoxy-3A-Ethyl-9-((2S,6S,8S)-4-Ethyl-8-(Methoxycarbonyl)-1,3,6,7,8,9-Hexahydro-2,6-Methanoazecino[4,3-B]Indol-8-Yl)-5-Hydroxy-8-Methoxy-6-Methyl-3A,3A1,4,5,5A,6,11 methyl (2beta,3beta,4beta,5alpha,12beta,19alpha)-4-(acetyloxy)-15-[(6R,8S)-4-ethyl-8-(methoxycarbonyl)-1,3,6,7,8,9-hexahydro-2,6-methanoazecino[4,3-b]indol-8-yl]-3-hydroxy-16-methoxy-1-methyl-6,7-didehydroaspidospermidine-3-carboxylate
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CAS | 125317-39-7
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EINECS | 639-264-2 |
InChI | InChI=1/C45H54N4O8/c1-8-27-19-28-22-44(40(51)55-6,36-30(25-48(23-27)24-28)29-13-10-11-14-33(29)46-36)32-20-31-34(21-35(32)54-5)47(4)38-43(31)16-18-49-17-12-15-42(9-2,37(43)49)39(57-26(3)50)45(38,53)41(52)56-7/h10-15,19-21,28,37-39,46,53H,8-9,16-18,22-25H2,1-7H3/t28-,37-,38+,39+,42+,43+,44-,45-/m0/s1 |
InChIKey | PMDHUNWDGZSEMN-WTUOTUPFSA-N |
VINORELBINE RELATED COMPOUND A4-O-DEACETYLVINORELBINE TARTRATE USP STANDARD - Physico-chemical Properties
Molecular Formula | C53H66N4O20
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Molar Mass | 1079.11 |
Density | 1.36g/cm3 |
Melting Point | 181-183°C |
Specific Rotation(α) | D20 +52.4° (c = 0.3 in CHCl3) |
Solubility | Soluble in methanol and dimethyl sulfoxide. |
Appearance | White crystal |
Color | off-white |
Storage Condition | 2-8°C |
Stability | Light Sensitive, Temperature Sensitive |
Refractive Index | 1.675 |
Physical and Chemical Properties | White or white-like powder or crystalline powder, odorless. |
VINORELBINE RELATED COMPOUND A4-O-DEACETYLVINORELBINE TARTRATE USP STANDARD - Risk and Safety
Hazard Symbols | Xi - Irritant
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Risk Codes | 43 - May cause sensitization by skin contact
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Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
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UN IDs | UN 1544PSN1 6.1 / PGII |
WGK Germany | 3 |
HS Code | 29339900 |
VINORELBINE RELATED COMPOUND A4-O-DEACETYLVINORELBINE TARTRATE USP STANDARD - Reference
Reference Show more | 1. Li Junbo, Yang Jinxiang, Yang Xiaoli, et al. Eosin Y probe fading spectrophotometric determination of vinorelbine [J]. Analytical Laboratory, 2014, 033(007):828-830. 2. Bian Jing, Zhang Penghui, Li Jiajia. Mechanism of aspirin combined with vinorelbine on MCF-7 of human breast cancer cells [J]. Northwest Journal of Pharmacy, 2021,36(01):52-56. |
VINORELBINE RELATED COMPOUND A4-O-DEACETYLVINORELBINE TARTRATE USP STANDARD - Introduction
Vinorelbine Ditartrate(Tartaric Acid Chongqing Ray-Bonn) is an organic Acid with the chemical formula C4H6O6. The following is a detailed description of its nature, use, preparation and safety information:
Nature:
- Vinorelbine Ditartrate is a colorless crystal or crystalline powder, soluble in water and ethanol, and slightly soluble in ether. Its solution is acidic.
-It is a chiral molecule, there are two optical isomers of L-tartaric acid and D-tartaric acid.
Use:
- Vinorelbine Ditartrate is widely used in the food industry as a sour taste regulator, antioxidant, stabilizer and chelating agent. It is often used in beverages, wines, jams, jellies, pastries, salad dressings and other foods to provide sourness and increase taste.
-It is also an important raw material for the pharmaceutical industry, for the preparation of drugs, enzymes and certain chemical reagents.
Preparation Method:
- Vinorelbine Ditartrate can be prepared by fermentation or synthesis.
-fermentation method is the natural production of L-tartaric acid microorganisms (such as yeast) culture under suitable conditions, the use of fructose fermentation, the production of L-tartaric acid. The synthetic rule uses the reaction of citric acid with potassium tartrate to give Vinorelbine Ditartrate.
Safety Information:
- Vinorelbine Ditartrate is considered safe under normal use.
-As an organic acid, it may be irritating to the skin and eyes. If it comes into contact with the skin or eyes, rinse immediately with water.
-During use, attention should be paid to prevent inhalation or swallowing, and avoid contact with high temperature or fire sources.
-During storage, Vinorelbine Ditartrate should be kept in a dry, ventilated place away from direct sunlight.
Last Update:2024-04-09 01:59:57